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COL-adjusted ranking

Best Cities for Pharmacists by Take-Home Pay

The cities that pay Pharmacists the most on paper aren't usually the best deals once rent and prices are factored in. Rochester ranks first with a COL-adjusted equivalent of $180,852/year, better purchasing power than Napa's higher nominal pay of $200,580. The table below uses BLS OEWS May 2025 salary data and BEA Regional Price Parities.

Highest nominal pay

#1 Napa$200,580
#2 San Jose-Sunnyvale-Santa Clara$199,040
#3 San Francisco-Oakland-Fremont$177,410

Best purchasing power

#1 Rochester$180,852
#2 San Jose-Sunnyvale-Santa Clara$180,257
#3 Florence$178,656

Top 25 metros by purchasing power

Ranked by COL-adjusted salary. Metros with fewer than 100 employed pharmacists excluded.

Rank
Metro
Nominal
COL-adj.
#1
Rochester
10% rent burden
$164,250
$180,852
#2
$199,040
$180,257
#3
Florence
8% rent burden
$155,020
$178,656
#4
Napa
17% rent burden
$200,580
$178,214
#5
Duluth
10% rent burden
$154,860
$174,451
#6
Yuma
10% rent burden
$161,630
$174,339
#7
La Crosse-Onalaska
9% rent burden
$159,020
$173,281
#8
Mankato
9% rent burden
$157,010
$172,633
#9
Spartanburg
9% rent burden
$153,610
$168,710
#10
Midland
13% rent burden
$161,260
$168,365
#11
St. Cloud
10% rent burden
$147,530
$168,356
#12
Dubuque
9% rent burden
$145,390
$166,483
#13
Redding
11% rent burden
$166,800
$165,673
#14
Fresno
12% rent burden
$169,160
$165,583
#15
Ann Arbor
12% rent burden
$166,350
$164,899
#16
Fort Wayne
9% rent burden
$152,530
$164,773
#17
Killeen-Temple
10% rent burden
$149,790
$164,370
#18
Jackson
11% rent burden
$140,540
$164,336
#19
Terre Haute
9% rent burden
$144,160
$164,191
#20
Cape Girardeau
8% rent burden
$141,250
$164,092
#21
Corvallis
11% rent burden
$170,470
$163,882
#22
Sioux Falls
9% rent burden
$148,330
$163,665
#23
Lincoln
9% rent burden
$149,590
$163,344
#24
Salem
11% rent burden
$169,210
$163,251
#25
Waco
8% rent burden
$150,710
$162,842

COL-adjusted = nominal salary divided by (BEA RPP divided by 100). Rent burden = annual 2BR FMR as % of nominal salary. Sources: BLS OEWS May 2025, BEA Regional Price Parities, HUD Fair Market Rents.

Common questions

What does "COL-adjusted pay" mean for Pharmacists?

COL-adjusted pay divides the BLS median salary by the BEA Regional Price Parity index (100 = national average). A salary of $200,580 in a city with RPP 120 has the same purchasing power as $167,150 at national average prices.

Why doesn't New York or San Francisco top this list?

Both cities pay above-average salaries, but rent and everyday costs eat most of that premium. A pharmacists in New York might earn 30% more but pay 60-80% more in rent. The net result is often less purchasing power than mid-cost metros.

How is purchasing power calculated?

Purchasing power equals nominal median salary divided by (BEA RPP divided by 100). BEA's Regional Price Parities measure relative price levels across metro areas, updated annually from the National Income and Product Accounts.

What's the most affordable metro for Pharmacists?

Florence has one of the lowest rent burdens for Pharmacists in this dataset. HUD FMR for a 2-bedroom is $1,098/month, with a median salary of $155,020.

Where do Pharmacists get paid the most in nominal terms?

Napa pays the highest nominal median salary at $200,580/year, per BLS OEWS May 2025. But check the COL-adjusted column before accepting any relocation offer.

National salary breakdown for PharmacistsView →How to become a pharmacistsGuide →Compare two cities side by sideCompare →