Nurse Practitioners Salary
In Mississippi, nurse practitioners earn $124,730 at the median, or about $59.96 an hour. The range runs from $99K at the entry level to $157K for experienced workers. Cost of living is below average (RPP 88.9), which stretches that salary to about $140,304 in buying power. Rent on a 2-bedroom averages $1,077/month, or 14.2% of estimated take-home pay.
Statewide average. Salary and cost of living vary significantly across Mississippi. Jump to a metro for precise data:
Where the paycheck goes
What $125K actually covers in Mississippi, month by month
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What this looks like in Mississippi
Nurse practitioners pay in Mississippi tracks closely to the national median, $125K locally vs. $132K nationwide, a 6% difference. Housing is manageable: a 2-bedroom at the HUD median costs $1,077/month, 14.3% of take-home, well inside the 30% guideline. Regional Price Parity sits at 88.9 (national = 100), meaning everyday costs run about 11% cheaper here. Your dollar stretches further than the headline salary suggests. Use the affordability calculator above to model your specific situation.
Compensation breakdown
Annual earnings by percentile, Mississippi
Entry-level nurse practitioners (10th percentile) start around $99K. Mid-career wages sit at $125K. Top earners bring in $157K or more, a $58K spread from bottom to top.
Nurse Practitioners salary by metro in Mississippi
3 metro areas with BLS data, ranked by median pay
| Metro area | Median salary | vs. state | Employment |
|---|---|---|---|
| Gulfport-Biloxi | $128K | +3% | 600 |
| Jackson | $125K | +0% | 1,310 |
| Hattiesburg | $113K | -9% | 340 |
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BLS updates this data annually. We'll email you when Mississippi numbers change.
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Quick answers
The stuff people actually ask about this job
Can a nurse practitioner afford a 2BR apartment alone in Mississippi?
Yes — at the median salary of $125K, rent takes 14.3% of take-home pay. A 2-bedroom at the HUD Fair Market Rent runs $1,077/month. That stays under the 30% guideline most financial planners use.
What’s the entry-level salary for nurse practitioners in Mississippi?
The 10th-percentile wage — what new nurse practitioners typically earn — is $99K/year. Take-home on that works out to about $6,103/month. At HUD’s $1,077/month FMR, rent would take 18% of that take-home — manageable on an entry-level income.
Is nurse practitioner a high-paying job in Mississippi?
Pay here is roughly in line with the national average — $125K locally vs. $132K nationally, a 6% difference.
How does Mississippi compare to the national average for nurse practitioners?
Mississippi pays $125K median vs. the U.S. average of $132K — that’s -6%. After adjusting for local cost of living (RPP 88.9), the purchasing-power equivalent is $140K — still ahead of the national median.
How much do nurse practitioners make in Mississippi?
The median is $124,730 a year, that works out to about $60 an hour. But the range is wide: entry-level workers start around $98,780, and experienced nurse practitioners can clear $156,830. These are BLS numbers, based on employer-reported data, not self-reported surveys.
Is $125K enough to live in Mississippi?
On that salary, you'd take home roughly $7,512/month after taxes. A 2-bedroom here rents for about $1,077/month, which eats 14.3% of your paycheck. That's under the 30% guideline most financial planners use, so the numbers work.
How far does a nurse practitioners salary go in Mississippi?
Mississippi has a Regional Price Parity of 88.9 (100 is the national average). That's below average, your money stretches further here than the raw salary number suggests. After cost-of-living adjustment, the median nurse practitioners salary is worth about $140,304 in national-average purchasing power.
Where do nurse practitioners get paid the most?
The table above ranks every state by median pay for this role. Keep in mind that the highest-paying states tend to have the highest costs of living, so the top salary doesn't always mean the most money in your pocket.