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Nurse Practitioners Salary

in Mississippi

In Mississippi, nurse practitioners earn $124,730 at the median, or about $59.96 an hour. The range runs from $99K at the entry level to $157K for experienced workers. Cost of living is below average (RPP 88.9), which stretches that salary to about $140,304 in buying power. Rent on a 2-bedroom averages $1,077/month, or 14.2% of estimated take-home pay.

Statewide average. Salary and cost of living vary significantly across Mississippi. Jump to a metro for precise data:

$125K
Median annual
$59.96/hr
Hourly rate
$99K
Entry level (10th %)
$157K
Senior level (90th %)

So what does $125K get you in Mississippi?

Estimated monthly take-home$7,512/mo
Median 2BR rent-$1,077/mo
Rent as % of take-home14.3% (within guideline)
Cost-of-living adjusted salary$140,304/yr
Monthly remaining after rent$6,435/mo

About nurse practitioners

Education: Master's degree
U.S. employed: 323,040
Mississippi employed: 4,690
Category: Healthcare

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What this looks like in Mississippi

Nurse practitioners pay in Mississippi tracks closely to the national median, $125K locally vs. $132K nationwide, a 6% difference. Housing is manageable: a 2-bedroom at the HUD median costs $1,077/month, 14.3% of take-home, well inside the 30% guideline. Regional Price Parity sits at 88.9 (national = 100), meaning everyday costs run about 11% cheaper here. Your dollar stretches further than the headline salary suggests. Use the affordability calculator above to model your specific situation.

Compensation breakdown

Annual earnings by percentile, Mississippi

Bar chart showing Nurse Practitioners salary percentiles in Mississippi: 10th percentile $98,780, 25th percentile $106,660, median $124,730, 75th percentile $134,020, 90th percentile $156,830. Source: Bureau of Labor Statistics.10th$99K25th$107KMedian$125K75th$134K90th$157K
Bar chart showing Nurse Practitioners salary percentiles in Mississippi: 10th percentile $98,780, 25th percentile $106,660, median $124,730, 75th percentile $134,020, 90th percentile $156,830. Source: Bureau of Labor Statistics.

Entry-level nurse practitioners (10th percentile) start around $99K. Mid-career wages sit at $125K. Top earners bring in $157K or more, a $58K spread from bottom to top.

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Nurse Practitioners salary by metro in Mississippi

3 metro areas with BLS data, ranked by median pay

Metro areaMedian salaryvs. stateEmployment
Gulfport-Biloxi$128K+3%600
Jackson$125K+0%1,310
Hattiesburg$113K-9%340

Compare to other states

Track nurse practitioners salary changes

BLS updates this data quarterly. We'll email you when Mississippi numbers change.

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Frequently asked questions

Can a nurse practitioner afford a 2BR apartment alone in Mississippi?

Yes — at the median salary of $125K, rent takes 14.3% of take-home pay. A 2-bedroom at the HUD Fair Market Rent runs $1,077/month. That stays under the 30% guideline most financial planners use.

What’s the entry-level salary for nurse practitioners in Mississippi?

The 10th-percentile wage — what new nurse practitioners typically earn — is $99K/year. Take-home on that works out to about $5,927/month. At HUD’s $1,077/month FMR, rent would take 18% of that take-home — manageable on an entry-level income.

Is nurse practitioner a high-paying job in Mississippi?

Pay here is roughly in line with the national average — $125K locally vs. $132K nationally, a 6% difference.

How does Mississippi compare to the national average for nurse practitioners?

Mississippi pays $125K median vs. the U.S. average of $132K — that’s -6%. After adjusting for local cost of living (RPP 88.9), the purchasing-power equivalent is $140K — still ahead of the national median.

How much do nurse practitioners make in Mississippi?

The median is $124,730 a year, that works out to about $60 an hour. But the range is wide: entry-level workers start around $98,780, and experienced nurse practitioners can clear $156,830. These are BLS numbers, based on employer-reported data, not self-reported surveys.

Is $125K enough to live in Mississippi?

On that salary, you'd take home roughly $7,512/month after taxes. A 2-bedroom here rents for about $1,077/month, which eats 14.3% of your paycheck. That's under the 30% guideline most financial planners use, so the numbers work.

How far does a nurse practitioners salary go in Mississippi?

Mississippi has a Regional Price Parity of 88.9 (100 is the national average). That's below average, your money stretches further here than the raw salary number suggests. After cost-of-living adjustment, the median nurse practitioners salary is worth about $140,304 in national-average purchasing power.

Where do nurse practitioners get paid the most?

The table above ranks every state by median pay for this role. Keep in mind that the highest-paying states tend to have the highest costs of living, so the top salary doesn't always mean the most money in your pocket.

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