Nurse Practitioners Salary
In South Carolina, nurse practitioners earn $123,290 at the median, or about $59.28 an hour. The range runs from $97K at the entry level to $160K for experienced workers. Cost of living is below average (RPP 93.17), which stretches that salary to about $132,328 in buying power. Rent on a 2-bedroom averages $1,263/month, or 16.9% of estimated take-home pay.
Statewide average. Salary and cost of living vary significantly across South Carolina. Jump to a metro for precise data:
So what does $123K get you in South Carolina?
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What this looks like in South Carolina
Nurse practitioners pay in South Carolina tracks closely to the national median, $123K locally vs. $132K nationwide, a 7% difference. Housing is manageable: a 2-bedroom at the HUD median costs $1,263/month, 17.1% of take-home, well inside the 30% guideline. Regional Price Parity sits at 93.17 (national = 100), meaning everyday costs run about 7% cheaper here. Your dollar stretches further than the headline salary suggests. Use the affordability calculator above to model your specific situation.
Compensation breakdown
Annual earnings by percentile, South Carolina
Entry-level nurse practitioners (10th percentile) start around $97K. Mid-career wages sit at $123K. Top earners bring in $160K or more, a $63K spread from bottom to top.
Nurse Practitioners salary by metro in South Carolina
8 metro areas with BLS data, ranked by median pay
| Metro area | Median salary | vs. state | Employment |
|---|---|---|---|
| Charleston-North Charleston | $128K | +4% | 1,050 |
| Florence | $122K | -1% | 270 |
| Myrtle Beach-Conway-North Myrtle Beach | $121K | -2% | 260 |
| Spartanburg | $121K | -2% | 260 |
| Greenville-Anderson-Greer | $119K | -3% | 1,120 |
| Hilton Head Island-Bluffton-Port Royal | $119K | -3% | 260 |
| Columbia | $118K | -4% | 920 |
| Sumter | $112K | -9% | 80 |
Compare to other states
Track nurse practitioners salary changes
BLS updates this data quarterly. We'll email you when South Carolina numbers change.
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Frequently asked questions
Can a nurse practitioner afford a 2BR apartment alone in South Carolina?
Yes — at the median salary of $123K, rent takes 17.1% of take-home pay. A 2-bedroom at the HUD Fair Market Rent runs $1,263/month. That stays under the 30% guideline most financial planners use.
What’s the entry-level salary for nurse practitioners in South Carolina?
The 10th-percentile wage — what new nurse practitioners typically earn — is $97K/year. Take-home on that works out to about $5,825/month. At HUD’s $1,263/month FMR, rent would take 22% of that take-home — manageable on an entry-level income.
Is nurse practitioner a high-paying job in South Carolina?
Pay here is roughly in line with the national average — $123K locally vs. $132K nationally, a 7% difference.
How does South Carolina compare to the national average for nurse practitioners?
South Carolina pays $123K median vs. the U.S. average of $132K — that’s -7%. After adjusting for local cost of living (RPP 93.17), the purchasing-power equivalent is $132K — still ahead of the national median.
How much do nurse practitioners make in South Carolina?
The median is $123,290 a year, that works out to about $59 an hour. But the range is wide: entry-level workers start around $97,080, and experienced nurse practitioners can clear $160,170. These are BLS numbers, based on employer-reported data, not self-reported surveys.
Is $123K enough to live in South Carolina?
On that salary, you'd take home roughly $7,397/month after taxes. A 2-bedroom here rents for about $1,263/month, which eats 17.1% of your paycheck. That's under the 30% guideline most financial planners use, so the numbers work.
How far does a nurse practitioners salary go in South Carolina?
South Carolina has a Regional Price Parity of 93.17 (100 is the national average). That's below average, your money stretches further here than the raw salary number suggests. After cost-of-living adjustment, the median nurse practitioners salary is worth about $132,328 in national-average purchasing power.
Where do nurse practitioners get paid the most?
The table above ranks every state by median pay for this role. Keep in mind that the highest-paying states tend to have the highest costs of living, so the top salary doesn't always mean the most money in your pocket.