Top Paying Jobs in Sioux Falls, SD-MN (2026)
Sioux Falls, SD-MN has 220 jobs across diverse industries. The highest-paying occupations include Nurse Anesthetists ($221,020), Pediatricians, General ($217,990), Family Medicine Physicians ($217,460). The cost of living index is 90.63 (national average = 100). Median 2-bedroom rent is $1,156/month.
$144K
Avg. median salary
90.63
Cost of living index
$1,156
Median 2BR rent
N/A
Population
Highest paying careers in Sioux Falls
| Rank | Occupation | Category | Median salary | Hourly |
|---|---|---|---|---|
| 1 | Nurse Anesthetists | Healthcare | $221K | $106.26/hr |
| 2 | Pediatricians, General | Healthcare | $218K | $104.8/hr |
| 3 | Family Medicine Physicians | Healthcare | $217K | $104.55/hr |
| 4 | Architectural and Engineering Managers | Management | $171K | $82.21/hr |
| 5 | Dentists, General | Healthcare | $171K | $82.15/hr |
| 6 | Computer and Information Systems Managers | Management | $169K | $81.08/hr |
| 7 | Financial Managers | Management | $165K | $79.45/hr |
| 8 | Marketing Managers | Management | $145K | $69.9/hr |
| 9 | Computer Network Architects | Technology | $144K | $69.31/hr |
| 10 | Pharmacists | Healthcare | $143K | $68.75/hr |
| 11 | General and Operations Managers | Management | $139K | $66.8/hr |
| 12 | Sales Managers | Management | $135K | $64.71/hr |
| 13 | Managers, All Other | Management | $132K | $63.32/hr |
| 14 | Nurse Practitioners | Healthcare | $131K | $62.78/hr |
| 15 | Physician Assistants | Healthcare | $128K | $61.6/hr |
| 16 | Optometrists | Healthcare | $127K | $60.88/hr |
| 17 | Sales Representatives, Wholesale and Manufacturing, Technical and Scientific Products | Sales | $122K | $58.56/hr |
| 18 | Medical and Health Services Managers | Management | $121K | $58.11/hr |
| 19 | Training and Development Managers | Management | $121K | $58.06/hr |
| 20 | Personal Financial Advisors | Business & Finance | $121K | $57.97/hr |
| 21 | Human Resources Managers | Management | $117K | $56.11/hr |
| 22 | Construction Managers | Management | $116K | $55.65/hr |
| 23 | Computer Occupations, All Other | Technology | $111K | $53.38/hr |
| 24 | First-Line Supervisors of Non-Retail Sales Workers | Sales | $108K | $52.14/hr |
| 25 | Sales Engineers | Sales | $107K | $51.65/hr |
Affordability snapshot: Sioux Falls
Cost of living vs. national average-9.4% less expensive
Studio apartment (FMR)$/mo
1-bedroom apartment (FMR)$/mo
2-bedroom apartment (FMR)$1,156/mo
3-bedroom apartment (FMR)$/mo
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After federal and state taxes