Top Paying Jobs in St. Louis, MO-IL (2026)
St. Louis, MO-IL has 110 jobs across diverse industries. The highest-paying occupations include Pediatricians, General ($211,070), Physicians, Pathologists ($199,990), Nurse Anesthetists ($192,070). The cost of living index is 95.09 (national average = 100). Median 2-bedroom rent is $1,218/month.
$147K
Avg. median salary
95.09
Cost of living index
$1,218
Median 2BR rent
N/A
Population
Highest paying careers in St. Louis
| Rank | Occupation | Category | Median salary | Hourly |
|---|---|---|---|---|
| 1 | Pediatricians, General | Healthcare | $211K | $101.47/hr |
| 2 | Physicians, Pathologists | Healthcare | $200K | $96.15/hr |
| 3 | Nurse Anesthetists | Healthcare | $192K | $92.34/hr |
| 4 | Physicists | Science | $180K | $86.75/hr |
| 5 | Chief Executives | Management | $173K | $82.98/hr |
| 6 | Natural Sciences Managers | Management | $161K | $77.62/hr |
| 7 | Judges, Magistrate Judges, and Magistrates | Legal | $156K | $75.1/hr |
| 8 | Architectural and Engineering Managers | Management | $155K | $74.57/hr |
| 9 | Computer and Information Systems Managers | Management | $155K | $74.4/hr |
| 10 | Physician Assistants | Healthcare | $140K | $67.42/hr |
| 11 | Financial Managers | Management | $140K | $67.42/hr |
| 12 | Pharmacists | Healthcare | $138K | $66.22/hr |
| 13 | Psychologists, All Other | Science | $137K | $65.82/hr |
| 14 | Purchasing Managers | Management | $134K | $64.53/hr |
| 15 | Optometrists | Healthcare | $131K | $62.8/hr |
| 16 | Nurse Practitioners | Healthcare | $129K | $62.21/hr |
| 17 | Human Resources Managers | Management | $129K | $61.79/hr |
| 18 | Lawyers | Legal | $128K | $61.57/hr |
| 19 | Actuaries | Technology | $128K | $61.44/hr |
| 20 | Advertising and Promotions Managers | Management | $128K | $61.38/hr |
| 21 | Podiatrists | Healthcare | $127K | $61.18/hr |
| 22 | Chemical Engineers | Engineering | $127K | $61.11/hr |
| 23 | Administrative Law Judges, Adjudicators, and Hearing Officers | Legal | $127K | $61.09/hr |
| 24 | Managers, All Other | Management | $127K | $61.09/hr |
| 25 | Marketing Managers | Management | $126K | $60.54/hr |
Affordability snapshot: St. Louis
Cost of living vs. national average-4.9% less expensive
Studio apartment (FMR)$/mo
1-bedroom apartment (FMR)$/mo
2-bedroom apartment (FMR)$1,218/mo
3-bedroom apartment (FMR)$/mo
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After federal and state taxes