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Healthcare

Registered Nurses Salary

in Missouri

Registered Nurses in Missouri make a median of $81,780 a year, or about $39.32 an hour. The range runs from $63K at the entry level to $104K for experienced workers. Cost of living is below average (RPP 88.97), which stretches that salary to about $91,919 in buying power. Rent on a 2-bedroom averages $1,097/month, or 21.2% of estimated take-home pay.

Statewide average. Salary and cost of living vary significantly across Missouri. Jump to a metro for precise data:

$82K
Median annual
$39.32/hr
Hourly rate
$63K
Entry level (10th %)
$104K
Senior level (90th %)

So what does $82K get you in Missouri?

Estimated monthly take-home$5,234/mo
Median 2BR rent-$1,097/mo
Rent as % of take-home21% (within guideline)
Cost-of-living adjusted salary$91,919/yr
Monthly remaining after rent$4,137/mo

About registered nurses

Education: Bachelor's degree
U.S. employed: 3,379,720
Missouri employed: 76,310
Category: Healthcare

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What this looks like in Missouri

Pay for registered nurses in Missouri runs about 16% below the U.S. median of $98K. Housing is manageable: a 2-bedroom at the HUD median costs $1,097/month, 21% of take-home, well inside the 30% guideline. Regional Price Parity sits at 88.97 (national = 100), meaning everyday costs run about 11% cheaper here. Your dollar stretches further than the headline salary suggests. Lower pay, lower costs, Missouri can be a reasonable trade-off for registered nursess who value affordability over top-dollar markets.

Compensation breakdown

Annual earnings by percentile, Missouri

Bar chart showing Registered Nurses salary percentiles in Missouri: 10th percentile $63,230, 25th percentile $76,050, median $81,780, 75th percentile $98,560, 90th percentile $104,390. Source: Bureau of Labor Statistics.10th$63K25th$76KMedian$82K75th$99K90th$104K
Bar chart showing Registered Nurses salary percentiles in Missouri: 10th percentile $63,230, 25th percentile $76,050, median $81,780, 75th percentile $98,560, 90th percentile $104,390. Source: Bureau of Labor Statistics.

Entry-level registered nurses (10th percentile) start around $63K. Mid-career wages sit at $82K. Top earners bring in $104K or more, a $41K spread from bottom to top.

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Registered Nurses salary by metro in Missouri

8 metro areas with BLS data, ranked by median pay

Metro areaMedian salaryvs. stateEmployment
Jefferson City$85K+4%1,910
Columbia$84K+3%3,680
St. Louis$83K+2%35,200
Kansas City$83K+2%29,650
Cape Girardeau$83K+1%1,470
Springfield$79K-3%6,820
St. Joseph$77K-6%1,490
Joplin$75K-8%2,670

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BLS updates this data quarterly. We'll email you when Missouri numbers change.

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Frequently asked questions

Can a registered nurse afford a 2BR apartment alone in Missouri?

Yes — at the median salary of $82K, rent takes 21% of take-home pay. A 2-bedroom at the HUD Fair Market Rent runs $1,097/month. That stays under the 30% guideline most financial planners use.

What’s the entry-level salary for registered nurses in Missouri?

The 10th-percentile wage — what new registered nurses typically earn — is $63K/year. Take-home on that works out to about $3,794/month. At HUD’s $1,097/month FMR, rent would take 29% of that take-home — manageable on an entry-level income.

Is registered nurse a high-paying job in Missouri?

Local pay runs 16% below the national median — $82K here vs. $98K nationally. Cost of living is 11% below the national average, which narrows that gap in real purchasing power.

How does Missouri compare to the national average for registered nurses?

Missouri pays $82K median vs. the U.S. average of $98K — that’s -16%. After adjusting for local cost of living (RPP 88.97), the purchasing-power equivalent is $92K — below the national median.

How much do registered nurses make in Missouri?

The median is $81,780 a year, that works out to about $39 an hour. But the range is wide: entry-level workers start around $63,230, and experienced registered nurses can clear $104,390. These are BLS numbers, based on employer-reported data, not self-reported surveys.

Is $82K enough to live in Missouri?

On that salary, you'd take home roughly $5,234/month after taxes. A 2-bedroom here rents for about $1,097/month, which eats 21% of your paycheck. That's under the 30% guideline most financial planners use, so the numbers work.

How far does a registered nurses salary go in Missouri?

Missouri has a Regional Price Parity of 88.97 (100 is the national average). That's below average, your money stretches further here than the raw salary number suggests. After cost-of-living adjustment, the median registered nurses salary is worth about $91,919 in national-average purchasing power.

Where do registered nurses get paid the most?

The table above ranks every state by median pay for this role. Keep in mind that the highest-paying states tend to have the highest costs of living, so the top salary doesn't always mean the most money in your pocket.

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