Registered Nurses Salary
Registered Nurses in Missouri make a median of $81,780 a year, or about $39.32 an hour. The range runs from $63K at the entry level to $104K for experienced workers. Cost of living is below average (RPP 88.97), which stretches that salary to about $91,919 in buying power. Rent on a 2-bedroom averages $1,097/month, or 21.2% of estimated take-home pay.
Statewide average. Salary and cost of living vary significantly across Missouri. Jump to a metro for precise data:
So what does $82K get you in Missouri?
About registered nurses
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What this looks like in Missouri
Pay for registered nurses in Missouri runs about 16% below the U.S. median of $98K. Housing is manageable: a 2-bedroom at the HUD median costs $1,097/month, 21% of take-home, well inside the 30% guideline. Regional Price Parity sits at 88.97 (national = 100), meaning everyday costs run about 11% cheaper here. Your dollar stretches further than the headline salary suggests. Lower pay, lower costs, Missouri can be a reasonable trade-off for registered nursess who value affordability over top-dollar markets.
Compensation breakdown
Annual earnings by percentile, Missouri
Entry-level registered nurses (10th percentile) start around $63K. Mid-career wages sit at $82K. Top earners bring in $104K or more, a $41K spread from bottom to top.
Registered Nurses salary by metro in Missouri
8 metro areas with BLS data, ranked by median pay
| Metro area | Median salary | vs. state | Employment |
|---|---|---|---|
| Jefferson City | $85K | +4% | 1,910 |
| Columbia | $84K | +3% | 3,680 |
| St. Louis | $83K | +2% | 35,200 |
| Kansas City | $83K | +2% | 29,650 |
| Cape Girardeau | $83K | +1% | 1,470 |
| Springfield | $79K | -3% | 6,820 |
| St. Joseph | $77K | -6% | 1,490 |
| Joplin | $75K | -8% | 2,670 |
Compare to other states
Track registered nurses salary changes
BLS updates this data quarterly. We'll email you when Missouri numbers change.
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Frequently asked questions
Can a registered nurse afford a 2BR apartment alone in Missouri?
Yes — at the median salary of $82K, rent takes 21% of take-home pay. A 2-bedroom at the HUD Fair Market Rent runs $1,097/month. That stays under the 30% guideline most financial planners use.
What’s the entry-level salary for registered nurses in Missouri?
The 10th-percentile wage — what new registered nurses typically earn — is $63K/year. Take-home on that works out to about $3,794/month. At HUD’s $1,097/month FMR, rent would take 29% of that take-home — manageable on an entry-level income.
Is registered nurse a high-paying job in Missouri?
Local pay runs 16% below the national median — $82K here vs. $98K nationally. Cost of living is 11% below the national average, which narrows that gap in real purchasing power.
How does Missouri compare to the national average for registered nurses?
Missouri pays $82K median vs. the U.S. average of $98K — that’s -16%. After adjusting for local cost of living (RPP 88.97), the purchasing-power equivalent is $92K — below the national median.
How much do registered nurses make in Missouri?
The median is $81,780 a year, that works out to about $39 an hour. But the range is wide: entry-level workers start around $63,230, and experienced registered nurses can clear $104,390. These are BLS numbers, based on employer-reported data, not self-reported surveys.
Is $82K enough to live in Missouri?
On that salary, you'd take home roughly $5,234/month after taxes. A 2-bedroom here rents for about $1,097/month, which eats 21% of your paycheck. That's under the 30% guideline most financial planners use, so the numbers work.
How far does a registered nurses salary go in Missouri?
Missouri has a Regional Price Parity of 88.97 (100 is the national average). That's below average, your money stretches further here than the raw salary number suggests. After cost-of-living adjustment, the median registered nurses salary is worth about $91,919 in national-average purchasing power.
Where do registered nurses get paid the most?
The table above ranks every state by median pay for this role. Keep in mind that the highest-paying states tend to have the highest costs of living, so the top salary doesn't always mean the most money in your pocket.
