Nurse Practitioners Salary
In Missouri, nurse practitioners earn $129,930 at the median, or about $62.47 an hour. The range runs from $101K at the entry level to $162K for experienced workers. Cost of living is below average (RPP 88.97), which stretches that salary to about $146,038 in buying power. Rent on a 2-bedroom averages $1,097/month, or 13.9% of estimated take-home pay.
Statewide average. Salary and cost of living vary significantly across Missouri. Jump to a metro for precise data:
So what does $130K get you in Missouri?
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What this looks like in Missouri
Nurse practitioners pay in Missouri tracks closely to the national median, $130K locally vs. $132K nationwide, a 2% difference. Housing is manageable: a 2-bedroom at the HUD median costs $1,097/month, 14% of take-home, well inside the 30% guideline. Regional Price Parity sits at 88.97 (national = 100), meaning everyday costs run about 11% cheaper here. Your dollar stretches further than the headline salary suggests. Use the affordability calculator above to model your specific situation.
Compensation breakdown
Annual earnings by percentile, Missouri
Entry-level nurse practitioners (10th percentile) start around $101K. Mid-career wages sit at $130K. Top earners bring in $162K or more, a $61K spread from bottom to top.
Nurse Practitioners salary by metro in Missouri
8 metro areas with BLS data, ranked by median pay
| Metro area | Median salary | vs. state | Employment |
|---|---|---|---|
| St. Louis | $132K | +1% | 3,430 |
| Kansas City | $131K | +1% | 2,730 |
| Cape Girardeau | $130K | +0% | 200 |
| Columbia | $129K | -1% | 330 |
| Jefferson City | $129K | -1% | 130 |
| St. Joseph | $129K | -1% | 140 |
| Joplin | $127K | -3% | 230 |
| Springfield | $126K | -3% | 660 |
Compare to other states
Track nurse practitioners salary changes
BLS updates this data quarterly. We'll email you when Missouri numbers change.
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Frequently asked questions
Can a nurse practitioner afford a 2BR apartment alone in Missouri?
Yes — at the median salary of $130K, rent takes 14% of take-home pay. A 2-bedroom at the HUD Fair Market Rent runs $1,097/month. That stays under the 30% guideline most financial planners use.
What’s the entry-level salary for nurse practitioners in Missouri?
The 10th-percentile wage — what new nurse practitioners typically earn — is $101K/year. Take-home on that works out to about $6,039/month. At HUD’s $1,097/month FMR, rent would take 18% of that take-home — manageable on an entry-level income.
Is nurse practitioner a high-paying job in Missouri?
Pay here is roughly in line with the national average — $130K locally vs. $132K nationally, a 2% difference.
How does Missouri compare to the national average for nurse practitioners?
Missouri pays $130K median vs. the U.S. average of $132K — that’s -2%. After adjusting for local cost of living (RPP 88.97), the purchasing-power equivalent is $146K — still ahead of the national median.
How much do nurse practitioners make in Missouri?
The median is $129,930 a year, that works out to about $62 an hour. But the range is wide: entry-level workers start around $100,650, and experienced nurse practitioners can clear $162,060. These are BLS numbers, based on employer-reported data, not self-reported surveys.
Is $130K enough to live in Missouri?
On that salary, you'd take home roughly $7,845/month after taxes. A 2-bedroom here rents for about $1,097/month, which eats 14% of your paycheck. That's under the 30% guideline most financial planners use, so the numbers work.
How far does a nurse practitioners salary go in Missouri?
Missouri has a Regional Price Parity of 88.97 (100 is the national average). That's below average, your money stretches further here than the raw salary number suggests. After cost-of-living adjustment, the median nurse practitioners salary is worth about $146,038 in national-average purchasing power.
Where do nurse practitioners get paid the most?
The table above ranks every state by median pay for this role. Keep in mind that the highest-paying states tend to have the highest costs of living, so the top salary doesn't always mean the most money in your pocket.
